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However, the signaling through TNFR1(p55) is complex and can also trigger a nuclear translocation of NF-kappa B and transcription of its target genes including both anti-apoptotic factors (e.g., IAPs, Bcl-2, Bcl-xL) and pro-inflammatory factors (e.g., cytokines, chemokines) (Figiel, 2008)
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For easier dosing calculations, many practitioners use: 2 mg vial + 2 mL bacteriostatic water = 1 mg/mL (1,000 mcg/mL) 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL (2,500 mcg/mL) Step 3: Draw Bacteriostatic Water Clean the rubber stopper of the bacteriostatic water vial with an alcohol prep pad