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high consumption of processed and refined food, with lack of dairy and meat-based food in diet, excessive consumption of alcohol, impaired absorption from the gastrointestinal tract or impaired storage and use by liver (1)

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Based on P‐scores, mazdutide ranked as the most favourable treatment for tolerability (0.90), followed by survodutide, while retatrutide and cotadutide had the highest risk of discontinuation due to adverse events