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evaluated the association between UA, cerebrospinal fluid biomarkers of AD and longitudinal cognitive decline in a follow-up period of 2.9 years ( n = 1064, including 271 healthy subjects, 596 with MCI, and 197 with AD) [112]

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It has been shown that truncations or modifications to this loop severely impair cobalt transport though the mechanism behind their interactions is still not well understood [67]