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The modern version of the e-cigarette was invented in China in 2003 and entered the international market in 2007(5)

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In addition to these, HLA-A*33, HLA-Aw*31, HLA-DR4, HLA-DR7, and HLA-DQB1*0303, among others, have been identified as risk factors for vitiligo in different samples.20,21 On the other hand, there are studies that correlate HLA-A*09 and HLA-Aw*19 with a lower risk for the disease.21 In Brazil, a study with patients from the southeast region demonstrated an association of HLA-A*02 and HLA-DRB1*07 with susceptibility to vitiligo.20 HLA-A*02 is also associated with risk in populations from China, India, Slovakia, and Northern Germany