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Here’s what the evidence suggests: Most research falls in the 500–1,500mg/day window, with 500–1,000mg/day appearing most reliable for liver health.5 10 68 Some trials have pushed up to 2,000mg/day, but there are no large dose-response studies to define an optimal dose

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Bus J Predictability of animal toxicity and carcinogenicity models for human risk: Part 2, Fishbowl