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Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation | Nature Communications

Meet the Veteran Jake is a 36-year-old sergeant in the Army who has always had a “sensitive gut.” His symptoms “really got bad” after he required a broad-spectrum antibiotic for a pneumonia he was treated for in Afghanistan

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In a rat OA model, pioglitazone-induced activation of PPARγ not only alleviated OA symptoms but also curbed expression of the ferroptosis marker ACSL4