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Furthermore, in 3xTg transgenic AD model mice and Caenorhabditis elegans models, betaine enhanced synaptic function and alleviated Aβ toxicity (192, 193)
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Extensive research involving transgenic mouse models (APP, 5×FAD, SAMP8), Drosophila melanogaster , and human clinical trials has demonstrated their potential in reducing Aβ burden, improving cognitive function, and restoring neuronal health
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