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Once established, mold not only grows but also produces metabolic by-products, including harmful compounds known as mycotoxins

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H 2 O 2 could also cause senescent cells to present a catabolic phenotype, primarily characterised by an increase of extracellular matrix-degrading enzymes (MMP-1, MMP-2, MMP-9, and ADAMTS-5), by a decrease of their suppressant (TIMPs) and by several proteoglycans, such as aggrecan, which is a major component of the myeloid nucleus [49]