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First, drought stress results in spatial difference in cell wall-associated pH between the two root zones, with the growing tip having a comparably lower pH to the elongation zone ( + -ATPase) induces cell wall (apoplastic) acidification, triggers expansins and cell wall relaxation (McQueen-Mason et al., 1992

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Restoring this ratio through dietary interventions or supplementation (e.g., folate, B-vitamins) has been a topic of interest in therapeutic strategies aimed at mitigating age-related decline in cellular function

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