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For this reason, RTKs have been among the most important molecular targets in oncology for over two decades, and their pharmacological inhibition has transformed the treatment of multiple malignancies [15,16]
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173 Another phase II clinical trial used sorafenib in combination with the cytotoxic agent dacarbazine (PubChem CID: 135398738) in leiomyosarcoma, synovial sarcoma, and MPNST patients
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