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416 Our study also reveals a mechanism of cell senescence, in which distinct effects of p53 and mTORC1 pathways on HSC ageing are governed by Wild-type p53-induced phosphatase 1 (Wip1), which negatively regulates several tumor suppressors and DDR pathways, 417 but also B lymphocyte maturation and tissue regeneration
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When drinking items that contain caffeine, such as coffee, green tea, and alcoholic beverages, I opt for a simple ‘2 for 1’ trick: 2 extra glasses of pure water for every dehydrating serving
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