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Constipation may also predispose bacteria to reach excessive populations, particularly Lactobacillus species that can execute tyrosine decarboxylation, L-DOPA by converting it into dopamine in the gut hence limiting its release into the bloodstream and causing motor fluctuations (Menozzi and Schapira, 2024)
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The intermediate-acting agents are lorazepam (12-h half-life), oxazepam (5-15 h), and alprazolam (6-26 h)
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