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Further, it inhibits 4-hydroxynoneal, a molecule produced in the body that negatively impacts cellular growth

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POR polymorphisms affect the amount of enzyme produced which may affect the activities of cytochrome P450 enzymes such as CYP1A2, 2C9, 2C19, 2D6, 3A4, and 3A5 [81–84], especially for compounds which are rapidly metabolized and where the electron transfer from NADPH via POR can be rate-limiting