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Further, experimental studies, in turn, should evaluate in more controlled settings, several aspects: (i) the role of acute and chronic PE in the molecular mechanisms that are underlying the onset of the disease and thus, test whether these positive changes in mitochondria, EAS enzymes and IS modulation reflects on the epidermis and in the melanocytes from vitiligo patients
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Inhibition of DHODH cannot increase the sensitivity of cells to FIN56-induced ferroptosis, while the decrease in CoQ cells was more sensitive to ferroptosis than DHODH knockout cells
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