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In adults, approved indications for growth hormone therapy include childhood-onset growth hormone deficiency, adult-onset hypopituitarism (underactive pituitary gland) due to pituitary or hypothalamic disease, AIDS-related wasting syndrome, and short bowel syndrome (18, 19)

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What community sources describe, explicitly as anecdote rather than guidance: Reports of pausing when headache, irritability, or GI symptoms persist or intensify