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After absorption, iron ions are oxidized by ceruloplasmin in the blood to trivalent iron ions, which then bind to transferrin receptor and enter the cells in the form of pinocytosis for hematopoietic cells

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Sources FDA — Wegovy (semaglutide) prescribing information, 2025 FDA — Ozempic (semaglutide) prescribing information, 2025 Mayo Clinic — Semaglutide (subcutaneous route) side effects Journal of the American Academy of Dermatology — Dermatologic findings associated with semaglutide use: a scoping review Pharmacy Times — Injection-site reactions and how to manage them Novo Nordisk — How to use your Wegovy pen Novo Nordisk — How to use your Ozempic pen Medical disclaimer: This article is for informational purposes only