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Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes

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In the clinical studies FDA identified — rectal enema dosing in healthy volunteers and ulcerative colitis patients, intra-articular injection for knee pain, intravesical injection for interstitial cystitis, and IV infusion in healthy subjects — no serious adverse events were reported

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