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Rilotumumab (AMG102, Amgen) Rilotumumab is a human monoclonal antibody designed to target HGF, preventing its interaction with the c-MET receptor and inhibiting the related cellular processes and in a Phase II clinical trial for gastric and esophagogastric junction cancers, rilotumumab combined with epirubicin, cisplatin, and capecitabine (ECX) demonstrated improvements in both progression-free survival (PFS) and overall survival (OS) for patients with high c-MET expression
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